Mallick Lab

~ translating multi-omic discovery into precision diagnostics ~
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All Publications 119 papers
2026 5 papers
  • Distinct molecular profiles associated with early vs late genome instability in cancer Lucie Gourmet, James Lam, Adam Pennycuick, Luis Zapata, Parag Mallick, Simon Walker-Samuel Scientific reports; 2026; 16(1)
  • Multi-Scale Tri-Modal Histology Dataset Integrating Tumor Morphology, Immune Patterns, and Clinical Outcomes★ SelectedPreprint Kyeong Joo Jung, Jianwei Qiu, Sanghee Cho, Elizabeth McDonough, Chrystal Chadwick, Soumya Ghose … Kyeong Joo Jung, Jianwei Qiu, Sanghee Cho, Elizabeth McDonough, Chrystal Chadwick, Soumya Ghose, Robert West, James D Brooks, Fiona Ginty, Raghu Machiraju, Parag Mallick bioRxiv : the preprint server for biology; 2026
  • Large-scale analysis of intact single molecule proteoforms of TauIn Press Z. Zhang, J. Joly, V. Budamagunta, B. Norman, M. Jouzi, R. Wang … Z. Zhang, J. Joly, V. Budamagunta, B. Norman, M. Jouzi, R. Wang, S. Guha, J. Sahota, S. Tan, P. Brereton, S. Temple, T. Bertucci, S. Lotz, D. Arnott, J. Lipka, N.J. Pandya, T. Wiederhold, D. Kirkpatrick, A. Rohou, J.E. Schwarz, A. Forton, E.R. Sartori, A. Huhmer, G. Kapp, J. Blanchard, K. Juneau, Parag Mallick Nature Methods; 2026
  • A straightforward, robust protocol for in-solution digest for bottom-up proteomicsIn Press Michelle Hori, Parag Mallick Methods in Molecular Biology; 2026
  • Using containerized ProteoWizard for data conversionIn Press Ravali Adusumilli, Parag Mallick Methods in Molecular Biology; 2026
2025 3 papers
  • A needed nomenclature for nucleosomes Michael-Christopher Keogh, Genevieve Almouzni, Andrew J Andrews, Karim-Jean Armache, Cheryl H Arrowsmith, Sung Hee Baek … Michael-Christopher Keogh, Genevieve Almouzni, Andrew J Andrews, Karim-Jean Armache, Cheryl H Arrowsmith, Sung Hee Baek, Mark T Bedford, Emily Bernstein, Jacques Côté, Yael David, John M Denu, Beat Fierz, Benjamin A Garcia, Karen C Glass, Or Gozani, Kristian Helin, Steven Henikoff, Ole N Jensen, Steven Z Josefowicz, Neil L Kelleher, Tatiana G Kutateladze, Herbert H Lindner, Chao Lu, Karolin Luger, Parag Mallick, Catherine A Musselman, Tom W Muir, Ljiljana Paša-Tolić, Robert Schneider, Xiaobing Shi, Yang Shi, Simone Sidoli, Lloyd M Smith, Jessica K Tyler, Cynthia Wolberger, Jerry L Workman, Brian D Strahl, Nicolas L Young Molecular cell; 2025; 85(19); 3554-3561
  • Annotation-Free Prediction of Cancer Cells and Glands and Spatial Analysis of Immune CellsPreprint Kyeong Joo Jung, Soumya Ghose, Sanghee Cho, Elizabeth McDonough, Chrystal Chadwick, Robert West … Kyeong Joo Jung, Soumya Ghose, Sanghee Cho, Elizabeth McDonough, Chrystal Chadwick, Robert West, James D Brooks, Dongjun Chung, Fiona Ginty, Raghu Machiraju, Parag Mallick bioRxiv : the preprint server for biology; 2025
  • Integrated Plasma and Tumor Proteomics of Nasopharyngeal Carcinoma in a Moroccan Cohort Ayman Reffai, Michelle Hori, Ravali Adusumilli, Abel Bermudez, Houssam Haddad, Nezha Tawfiq … Ayman Reffai, Michelle Hori, Ravali Adusumilli, Abel Bermudez, Houssam Haddad, Nezha Tawfiq, Sharon Pitteri, Mohcine Bennani Mechita, Parag Mallick International journal of molecular sciences; 2025; 26(12)
2024 5 papers
  • A Proteomic Analysis of Nasopharyngeal Carcinoma in a Moroccan Subpopulation Ayman Reffai, Michelle Hori, Ravali Adusumilli, Abel Bermudez, Abdelilah Bouzoubaa, Sharon Pitteri … Ayman Reffai, Michelle Hori, Ravali Adusumilli, Abel Bermudez, Abdelilah Bouzoubaa, Sharon Pitteri, Mohcine Bennani Mechita, Parag Mallick Cancers; 2024; 16(19)
  • AZGP1 deficiency promotes angiogenesis in prostate cancer Ru M Wen, Zhengyuan Qiu, G Edward W Marti, Eric E Peterson, Fernando Jose Garcia Marques, Abel Bermudez … Ru M Wen, Zhengyuan Qiu, G Edward W Marti, Eric E Peterson, Fernando Jose Garcia Marques, Abel Bermudez, Yi Wei, Rosalie Nolley, Nathan Lam, Alex LaPat Polasko, Chun-Lung Chiu, Dalin Zhang, Sanghee Cho, Grigorios Marios Karageorgos, Elizabeth McDonough, Chrystal Chadwick, Fiona Ginty, Kyeong Joo Jung, Raghu Machiraju, Parag Mallick, Laura Crowley, Jonathan R Pollack, Hongjuan Zhao, Sharon J Pitteri, James D Brooks Journal of translational medicine; 2024; 22(1); 383
  • Examination of the role of mutualism in immune evasion Lucie Gourmet, Simon Walker-Samuel, Parag Mallick Frontiers in oncology; 2024; 14; 1406744
  • Prospector Heads: Generalized Feature Attribution for Large Models & Data★ Selected Gautam Machiraju, Alexander Derry, Arjun Desai, Neel Guha, Amir-Hossein Karimi, James Zou … Gautam Machiraju, Alexander Derry, Arjun Desai, Neel Guha, Amir-Hossein Karimi, James Zou, Russ B Altman, Christopher Ré, Parag Mallick ICML'24: Proceedings of the 41st International Conference on Machine Learning; 2024; 34115 - 34144
  • The Temporal Evolution of Cancer HallmarksPreprint Lucie Gourmet, Daniele Ramazzoti, Parag Mallick, Simon Walker-Samuel, Luis Zapata bioRxiv; 2024
2023 3 papers
2022 5 papers
2021 5 papers
2020 4 papers
  • ImmunoGlobe: enabling systems immunology with a manually curated intercellular immune interaction network Michelle B Atallah, Varun Tandon, Kamir J Hiam, Hunter Boyce, Michelle Hori, Waleed Atallah … Michelle B Atallah, Varun Tandon, Kamir J Hiam, Hunter Boyce, Michelle Hori, Waleed Atallah, Matthew H Spitzer, Edgar Engleman, Parag Mallick BMC bioinformatics; 2020; 21(1); 346
  • Multicompartment modeling of protein shedding kinetics during vascularized tumor growth Gautam B Machiraju, Parag Mallick, Hermann B Frieboes Scientific reports; 2020; 10(1); 16709
  • PTR Explorer: An approach to identify and explore Post Transcriptional Regulatory mechanisms using proteogenomics Arunima Srivastava, Michael Sharpnack, Kun Huang, Parag Mallick, Raghu Machiraju Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing; 2020; 25; 475-486
  • Using information about the influence of nutrient diffusion on tumor evolution to enhance learning of patient trajectories Hunter Boyce, Parag Mallick Proceedings of the AAAI Fall 2020 Symposium on Physics-Guided AI to Accelerate Scientific Discovery; 2020
2019 4 papers
  • Geostatistical visualization of ecological interactions in tumors Hunter Bryan Boyce, Parag Mallick Proceedings. IEEE International Conference on Bioinformatics and Biomedicine; 2019; 2019; 2741-2749
  • Improving Precursor Selectivity in Data-Independent Acquisition Using Overlapping Windows Dario Amodei, Jarrett Egertson, Brendan X MacLean, Richard Johnson, Gennifer E Merrihew, Austin Keller … Dario Amodei, Jarrett Egertson, Brendan X MacLean, Richard Johnson, Gennifer E Merrihew, Austin Keller, Don Marsh, Olga Vitek, Parag Mallick, Michael J MacCoss Journal of the American Society for Mass Spectrometry; 2019; 30(4); 669-684
  • Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis Katrin Tiemann, Carolina Garri, Sang Bok Lee, Paymaneh D Malihi, Mincheol Park, Ruth M Alvarez … Katrin Tiemann, Carolina Garri, Sang Bok Lee, Paymaneh D Malihi, Mincheol Park, Ruth M Alvarez, Li Peng Yap, Parag Mallick, Jonathan E Katz, Mitchell E Gross, Kian Kani Oncogene; 2019; 38(16); 3003-3018
  • Semantic workflows for benchmark challenges: Enhancing comparability, reusability and reproducibility Arunima Srivastava, Ravali Adusumilli, Hunter Boyce, Daniel Garijo, Varun Ratnakar, Rajiv Mayani … Arunima Srivastava, Ravali Adusumilli, Hunter Boyce, Daniel Garijo, Varun Ratnakar, Rajiv Mayani, Thomas Yu, Raghu Machiraju, Yolanda Gil, Parag Mallick Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing; 2019; 24; 208-219
2018 11 papers
2017 9 papers
2016 9 papers
2015 8 papers
2014 3 papers
2013 3 papers
  • A physical sciences network characterization of non-tumorigenic and metastatic cells David B Agus, Jenolyn F Alexander, Wadih Arap, Shashanka Ashili, Joseph E Aslan, Robert H Austin … David B Agus, Jenolyn F Alexander, Wadih Arap, Shashanka Ashili, Joseph E Aslan, Robert H Austin, Vadim Backman, Kelly J Bethel, Richard Bonneau, Wei-Chiang Chen, Chira Chen-Tanyolac, Nathan C Choi, Steven A Curley, Matthew Dallas, Dhwanil Damania, Paul C W Davies, Paolo Decuzzi, Laura Dickinson, Luis Estevez-Salmeron, Veronica Estrella, Mauro Ferrari, Claudia Fischbach, Jasmine Foo, Stephanie I Fraley, Christian Frantz, Alexander Fuhrmann, Philippe Gascard, Robert A Gatenby, Yue Geng, Sharon Gerecht, Robert J Gillies, Biana Godin, William M Grady, Alex Greenfield, Courtney Hemphill, Barbara L Hempstead, Abigail Hielscher, W Daniel Hillis, Eric C Holland, Arig Ibrahim-Hashim, Tyler Jacks, Roger H Johnson, Ahyoung Joo, Jonathan E Katz, Laimonas Kelbauskas, Carl Kesselman, Michael R King, Konstantinos Konstantopoulos, Casey M Kraning-Rush, Peter Kuhn, Kevin Kung, Brian Kwee, Johnathon N Lakins, Guillaume Lambert, David Liao, Jonathan D Licht, Jan T Liphardt, Liyu Liu, Mark C Lloyd, Anna Lyubimova, Parag Mallick, John Marko, Owen J T McCarty, Deirdre R Meldrum, Franziska Michor, Shannon M Mumenthaler, Vivek Nandakumar, Thomas V O'Halloran, Steve Oh, Renata Pasqualini, Matthew J Paszek, Kevin G Philips, Christopher S Poultney, Kuldeepsinh Rana, Cynthia A Reinhart-King, Robert Ros, Gregg L Semenza, Patti Senechal, Michael L Shuler, Srimeenakshi Srinivasan, Jack R Staunton, Yolanda Stypula, Hariharan Subramanian, Thea D Tlsty, Garth W Tormoen, Yiider Tseng, Alexander van Oudenaarden, Scott S Verbridge, Jenny C Wan, Valerie M Weaver, Jonathan Widom, Christine Will, Denis Wirtz, Jonathan Wojtkowiak, Pei-Hsun Wu Scientific reports; 2013; 3; 1449
  • Anterior gradient 2 (AGR2): blood-based biomarker elevated in metastatic prostate cancer associated with the neuroendocrine phenotype Kian Kani, Paymaneh D Malihi, Yuqiu Jiang, Haiying Wang, Yixin Wang, Daniel L Ruderman … Kian Kani, Paymaneh D Malihi, Yuqiu Jiang, Haiying Wang, Yixin Wang, Daniel L Ruderman, David B Agus, Parag Mallick, Mitchell E Gross The Prostate; 2013; 73(3); 306-15
  • Characterizing deformability and surface friction of cancer cells Sangwon Byun, Sungmin Son, Dario Amodei, Nathan Cermak, Josephine Shaw, Joon Ho Kang … Sangwon Byun, Sungmin Son, Dario Amodei, Nathan Cermak, Josephine Shaw, Joon Ho Kang, Vivian C Hecht, Monte M Winslow, Tyler Jacks, Parag Mallick, Scott R Manalis Proceedings of the National Academy of Sciences of the United States of America; 2013; 110(19); 7580-5
2012 6 papers
  • A cross-platform toolkit for mass spectrometry and proteomics★ Selected Matthew C Chambers, Brendan Maclean, Robert Burke, Dario Amodei, Daniel L Ruderman, Steffen Neumann … Matthew C Chambers, Brendan Maclean, Robert Burke, Dario Amodei, Daniel L Ruderman, Steffen Neumann, Laurent Gatto, Bernd Fischer, Brian Pratt, Jarrett Egertson, Katherine Hoff, Darren Kessner, Natalie Tasman, Nicholas Shulman, Barbara Frewen, Tahmina A Baker, Mi-Youn Brusniak, Christopher Paulse, David Creasy, Lisa Flashner, Kian Kani, Chris Moulding, Sean L Seymour, Lydia M Nuwaysir, Brent Lefebvre, Frank Kuhlmann, Joe Roark, Paape Rainer, Suckau Detlev, Tina Hemenway, Andreas Huhmer, James Langridge, Brian Connolly, Trey Chadick, Krisztina Holly, Josh Eckels, Eric W Deutsch, Robert L Moritz, Jonathan E Katz, David B Agus, Michael MacCoss, David L Tabb, Parag Mallick Nature biotechnology; 2012; 30(10); 918-20
  • Cancer as a Multi-scale Complex Adaptive System Parag Mallick Assessment of Physical Sciences and Engineering Advances in Life Sciences and Oncology (APHELION) in Europe; 2012; 4-21
  • Investigation of acquired resistance to EGFR-targeted therapies in lung cancer using cDNA microarrays Kian Kani, Rafaella Sordella, Parag Mallick Methods in molecular biology (Clifton, N.J.); 2012; 795; 233-53
  • Quantitative proteomic profiling identifies protein correlates to EGFR kinase inhibition Kian Kani, Vitor M Faca, Lindsey D Hughes, Wenxuan Zhang, Qiaojun Fang, Babak Shahbaba … Kian Kani, Vitor M Faca, Lindsey D Hughes, Wenxuan Zhang, Qiaojun Fang, Babak Shahbaba, Roland Luethy, Jonathan Erde, Joanna Schmidt, Sharon J Pitteri, Qing Zhang, Jonathan E Katz, Mitchell E Gross, Sylvia K Plevritis, Martin W McIntosh, Anjali Jain, Samir Hanash, David B Agus, Parag Mallick Molecular cancer therapeutics; 2012; 11(5); 1071-81
  • Semi-Automatically Mapping Structured Sources into the Semantic Web Craig A. Knoblock, Pedro Szekely, Jose Luis Ambite, Aman Goel, Shubham Gupta, Maria Muslea … Craig A. Knoblock, Pedro Szekely, Jose Luis Ambite, Aman Goel, Shubham Gupta, Maria Muslea, Kristina Lerman, Parag Mallick Lecture Notes in Computer Science (The Semantic Web: Research and Applications); 2012; 7295; 375-390
  • Unexpected dissemination patterns in lymphoma progression revealed by serial imaging within a murine lymph node Ken Ito, Bryan Ronain Smith, Natesh Parashurama, Joon-Kee Yoon, Si Yeol Song, Cornelius Miething … Ken Ito, Bryan Ronain Smith, Natesh Parashurama, Joon-Kee Yoon, Si Yeol Song, Cornelius Miething, Parag Mallick, Scott Lowe, Sanjiv Sam Gambhir Cancer research; 2012; 72(23); 6111-8
2011 7 papers
2010 2 papers
2009 1 paper
  • Recommendations from the 2008 International Summit on Proteomics Data Release and Sharing Policy: the Amsterdam principles Henry Rodriguez, Mike Snyder, Mathias Uhlén, Phil Andrews, Ronald Beavis, Christoph Borchers … Henry Rodriguez, Mike Snyder, Mathias Uhlén, Phil Andrews, Ronald Beavis, Christoph Borchers, Robert J Chalkley, Sang Yun Cho, Katie Cottingham, Michael Dunn, Tomasz Dylag, Ron Edgar, Peter Hare, Albert J R Heck, Roland F Hirsch, Karen Kennedy, Patrik Kolar, Hans-Joachim Kraus, Parag Mallick, Alexey Nesvizhskii, Peipei Ping, Fredrik Pontén, Liming Yang, John R Yates, Stephen E Stein, Henning Hermjakob, Christopher R Kinsinger, Rolf Apweiler Journal of proteome research; 2009; 8(7); 3689-92
2008 4 papers
2007 1 paper
2006 6 papers
2005 5 papers
2004 1 paper
2003 1 paper
2002 5 papers
2000 3 papers